Difference Between Bone Deposition and Resorption | Bone Deposition vs Resorption


The key difference between bone deposition and resorption is that bone deposition is the process of depositing new bone matrix by the osteoblasts while bone resorption is the process by which osteoclasts break down the tissue in bones and release minerals to the blood.

Bone is a calcified piece of hard, whitish, living and growing tissue that makes the skeleton in humans and other vertebrates. It consists of different cell types including osteoblasts, osteocytes, osteoclasts, and bone lining cells. Bones change over their life span in order to protect the structural integrity of the skeletal system and balance the calcium and phosphorus in the body. Thus, this process is called bone remodeling. Bone resorption and bone deposition are the two major events of bone remodeling. Resorption occurs in old or damaged bones while creating new bone materials. Two types of bone cells are responsible for bone resorption and deposition phases of bone remodeling. They are osteoclasts and osteoblasts.

CONTENTS

1. Overview and Key Difference
2. What is Bone Deposition
3. What is Bone Resorption
4. Similarities Between Bone Deposition and Resorption
5. Side by Side Comparison – Bone Deposition and Resorption in Tabular Form
6. Summary

What is Bone Deposition

Bone deposition is one of the two main events of bone remodeling. It is the process of depositing new bone materials. Osteoblasts are the bone-forming cells that carry out bone deposition. They secrete an organic matrix that is rich in collagen protein.

Difference Between Bone Deposition and Resorption | Bone Deposition vs ResorptionFigure 01: Bone Deposition

Once hydroxyapatite is deposited on the secreted organic matrix, it becomes hardened bone. In other words, bone deposition can be defined as the deposition of hydroxyapatite on the bones.

What is Bone Resorption

Bone resorption is the second major event of bone remodeling. It is the process that breaks down old bones as well as damaged bones. Therefore, this prevents the accumulation of damaged bones in the new bones.

Difference Between Bone Deposition and Resorption | Bone Deposition vs ResorptionFigure 02: Bone Resorption

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