Difference Between Sorbitol and Mannitol


  • sorbitol vs mannitol
  • sorbitol vs mannitol structure
  • sorbitol and mannitol structure
  • mannitol or sorbitol
  • When synthesized, sorbitol appears as a crystalline white powder. The major pathway of production is the glucose reduction reaction in which the aldehyde group is converted into an alcohol group. This reaction requires NADH and occurs in the presence of a catalyst – aldose reductase. Glucose reduction is a pathway of polyol production in glucose metabolism.
    Difference Between Sorbitol and Mannitol
    Figure 01: Chemical Structure of Sorbitol There are several applications of sorbitol: as an artificial sweetener, as a laxative, as a bacterial culture media, in treating hyperkalaemia, in the manufacture of soft gel capsules, etc. Sorbitol is also useful in the cosmetic industry as a humectant and as a thickener. Besides, there are miscellaneous uses of sorbitol such as the manufacture of rocket fuel, production of biomass resources, etc.

    What is Mannitol?

    Mannitol is a sugar alcohol that is useful both as a sweetener and as a medication. Since it is poorly absorbed by the intestine, we can use mannitol in diabetic food. As a medication, we can use mannitol to decrease pressure in eyes and lower increased intracranial pressure. It can be administrated in the form of an injection in medical purposes.